HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-3-nitrobenzoic acid → 4-Chloro-3-nitrobenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-3-nitrobenzoic acid | HCID 7320 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 4-Chloro-3-nitrobenzoyl chloride | HCID 123477 | — |
Reaction Steps
To a solution of 14.1 g (0.07 mole) of 4-chloro-3-nitrobenzoic acid in 200 ml of dry benzene, 10 ml of thionyl chloride is added and the mixture is refluxed for 10 hours. The excess of thionyl chloride is removed in vacuo and the acid chloride is purified by repeated addition of fresh benzene and subsequent removal in vacuo.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04022901 |
| Source dataset | uspto-grants-1977_05 |
| ORD ID | ord-cf5164a0edd645ec8e6f169815b3910a |
| Source note | uspto-grants-1977_05 |