Dimethyl Sulfate → HCID 54044700, compound

Participants

Reaction Steps

To a solution of 31.5 g of 4-acetamido-3[1-acetyl-2-(2,6-dichlorobenzylidene)hydrazino] -1,2,4-triazole and 53.0 g of sodium carbonate in 400 ml of water is added dropwise, while stirring and cooling in an ice bath, 40 ml of dimethyl sulphate (2 h). After the addition the mixture was stirred for 2,5 h while cooling in ice and left overnight at room temperature. The obtained precipitate is collected and recrystallized twice from dioxane-isopropyl ether. Yield: 7.3 g, m.p. 167°-169° .

Provenance & Evidence