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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2397895Generated: October 30, 2026

1,3-Cyclohexanedione → HCID 70635761, compound

https://huagongshe.com/reaction/2397895

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-CyclohexanedioneHCID 10434—
Reactant2-CyanobenzaldehydeHCID 101209—
ReactantCarbamimidoyl-acetic acid ethyl esterHCID 4599837—
SolventEthanolHCID 702—
ProductHCID 70635761HCID 7063576149%

Reaction Steps

Upon heating a solution of 6.5 g of 2-cyanobenzaldehyde, 5.6 g of cyclohexane-1,3-dione and 6.5 g of amidinoacetic acid ethyl ester in 100 ml of ethanol for 5 hours, 2-amino-4-(2-cyanophenyl)- 1,4,5,6,7,8-hexahydro-5-oxoquinoline-3-carboxylic acid ethyl ester of melting point 165° C. (ethanol) is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04022898
Source datasetuspto-grants-1977_05
ORD IDord-7989ccb1c4924d5193d9249d72b96047
Source noteuspto-grants-1977_05