HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Anisoyl chloride → Benzamide, 4-methoxy-N-(1,2,3,4-tetrahydro-2-methylisoquinolin-5-yl)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Anisoyl chloride | HCID 7477 | — |
| Reactant | 2-Methyl-1,2,3,4-tetrahydroisoquinolin-5-amine | HCID 14171269 | — |
| Product | Benzamide, 4-methoxy-N-(1,2,3,4-tetrahydro-2-methylisoquinolin-5-yl)- | HCID 216594 | — |
Reaction Steps
5-Amino-2-methyl-1,2,3,4-tetrahydroisoquinoline was reacted with 4-methoxybenzoyl chloride according to the procedure of Example 19 to yield 5-(4-methoxybenzamido)2-methyl-1,2,3,4-tetrahydroisoquinoline; m.p. 169.5°-171.5° C. after purification from ethanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04022900 |
| Source dataset | uspto-grants-1977_05 |
| ORD ID | ord-59994bd7e854463bacb1389d968abc93 |
| Source note | uspto-grants-1977_05 |