HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Dimethoxybenzoyl chloride → Benzamide, 2,6-dimethoxy-N-(1,2,3,4-tetrahydro-2-methylisoquinolin-5-yl)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Dimethoxybenzoyl chloride | HCID 74810 | — |
| Reactant | 2-Methyl-1,2,3,4-tetrahydroisoquinolin-5-amine | HCID 14171269 | — |
| Product | Benzamide, 2,6-dimethoxy-N-(1,2,3,4-tetrahydro-2-methylisoquinolin-5-yl)- | HCID 216595 | — |
Reaction Steps
5-Amino-2-methyl-1,2,3,4-tetrahydroisoquinoline was reacted with 2,6-dimethoxybenzoyl chloride according to the procedure of Example 19 to yield 5-(2,6-dimethoxybenzamido)-2-methyl-1,2,3,4-tetrahydroisoquinoline; m.p. 191°-192° C. after recrystallization from benzene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04022900 |
| Source dataset | uspto-grants-1977_05 |
| ORD ID | ord-df11d3fcd1df411faa684c7e4a7721b6 |
| Source note | uspto-grants-1977_05 |