HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4,5-Trimethoxybenzoyl chloride → Benzamide, N-(1,2,3,4-tetrahydro-2-methylisoquinolin-5-yl)-2,4,5-trimethoxy-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4,5-Trimethoxybenzoyl chloride | HCID 2760809 | — |
| Reactant | 2-Methyl-1,2,3,4-tetrahydroisoquinolin-5-amine | HCID 14171269 | — |
| Product | Benzamide, N-(1,2,3,4-tetrahydro-2-methylisoquinolin-5-yl)-2,4,5-trimethoxy- | HCID 216596 | — |
Reaction Steps
5-Amino-2-methyl-1,2,3,4-tetrahydroisoquinoline was reacted with 2,4,5-trimethoxybenzoyl chloride according to the procedure of Example 19 to yield 5-(2,4,5-trimethoxybenzamido)-2-methyl-1,2,3,4-tetrahydroisoquinoline; m.p. 159°-160.5° C. after purification from ethanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04022900 |
| Source dataset | uspto-grants-1977_05 |
| ORD ID | ord-ecbe45762ab840158cd1cbf6233030f3 |
| Source note | uspto-grants-1977_05 |