Aluminium lithium hydride → HCID 22797560, compound

Participants

Reaction Steps

1α-Hydroxy-3β,24(S)-dibenzoyloxy-cholest-5-ene prepared in the same way as in Example 4, (B) was reduced with LiAlH4 in dry diethyl ether to form 1α,3β,24(S)-trihydroxy cholest-5-ene. This product (180 mg) was then reacted with 24 ml. of acetic anhydride and 75 ml. of pyridine at 95° C. for 3.5 hours. The product was treated in the same way as in Example 3, (A), and chromatographed through a column containing silica gel as a carrier to afford 195 mg of 1α,3β,24(S)-triacetoxy-cholest-5-ene.

Provenance & Evidence