HCID 11270016, compound → HCID 22797576, compound

Participants

Reaction Steps

The 1α,3β,24(S)-trihydroxycholesta-5,7-diene obtained in Example 16 was benzoylated in quite the same way as in Example 22, (A) to form 1α-hydroxy-3β,24(S)-dibenzoyloxycholesta-5,7-diene. 15 mg of this product was treated in quite the same way as in Example 25 to afford 1.5 mg of a product whose properties corresponded with 1α,24(S)-dihydroxycholecalciferol. From this, it was confirmed that the product obtained after the isomerization was 1α-hydroxy-24(S)-benzoyloxycholecalciferol-3β-benzoate.

Provenance & Evidence