HuagongsheHuagongshe Chemistry Print Report · For research reference only
17beta,19-Dihydroxy-1alphamethyl-4-androsten-3-one → 1alpha,7alpha-Dimethyl-4-androstene-3,17,19-trione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 17beta,19-Dihydroxy-1alphamethyl-4-androsten-3-one | HCID 22797425 | — |
| Reactant | 19-Hydroxy1alpha-methyl-4-androstene-3,17-dione | HCID 70584008 | — |
| Reactant | 17beta,19-Dihydroxy-1alpha,7alpha-dimethyl-4-androsten-3-one | HCID 70585453 | — |
| Product | 1alpha,7alpha-Dimethyl-4-androstene-3,17,19-trione | HCID 53879340 | — |
| Product | 1alpha-Methyl-4-androstene-3,17,19-trione | HCID 54386542 | — |
Reaction Steps
Substituting 17β,19-dihydroxy-1α,17α-dimethyl-4-androsten-3-one, 19-hydroxy-1α-methyl-4-androstene-3,17-dione, 17β,19-dihydroxy-1α,7α-dimethyl-4-androsten-3-one and 17β,19-dihydroxy-1α,6α,17α-trimethyl-4-androsten-3-one for the 17β,19-dihydroxy-1α-methyl-4-androsten-3-one above results in the preparation of 17β-hydroxy-1α,17α-dimethyl-4-androstene-3,19-dione, 1α-methyl-4-androstene-3,17,19-trione, 1α,7α-dimethyl-4-androstene-3,17,19-trione and 17β-hydroxy-1α,6α,17α-trimethyl-4-androstene-3,19-dione, respectively.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04022769 |
| Source dataset | uspto-grants-1977_05 |
| ORD ID | ord-c783a18f10bd4dc6aa04895a31a074fd |
| Source note | uspto-grants-1977_05 |