19-Hydroxytestosterone → 4-Androstene-17beta,19-diol

HRID 2397971Notes

Reaction equation

HRID 2397971 reaction equation
[OH:1][C@H:2]1[CH2:7][CH2:6][C@H:5]2[C@H:8]3[C@H:19]([CH2:20][CH2:21][C@:3]12[CH3:4])[C@:16]1([CH2:17][OH:18])[C:11](=[CH:12][C:13](=O)[CH2:14][CH2:15]1)[CH2:10][CH2:9]3.O[C@H]1CC[C@H]2[C@H]3[C@H](CC[C@]12C)[C@]1(CO)C(=CC(=O)C[C@@H]1C)CC3>>[CH3:4][C@:3]12[CH2:21][CH2:20][C@H:19]3[C@@H:8]([CH2:9][CH2:10][C:11]4[C@:16]3([CH2:17][OH:18])[CH2:15][CH2:14][CH2:13][CH:12]=4)[C@@H:5]1[CH2:6][CH2:7][C@@H:2]2[OH:1]

Participants

3

Reactant 2

HCID 15096819-HydroxytestosteroneHCID 2279742517beta,19-Dihydroxy-1alphamethyl-4-androsten-3-one

Product 1

HCID 109572354-Androstene-17beta,19-diol

Procedure

Substituting 17β,19-dihydroxy-4-androsten-3-one for the 17β,19-dihydroxy-1α-methyl-4-androsten-3-one above results in the preparation of 4-androstene-17β,19-diol.

Sources & evidence

ORD record
ord-921d21d180274021a7eefb45e8dd7f97
Source dataset
uspto-grants-1977_05
Patent number
US04022769

Reaction notes

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