4-Androstene-17beta,19-diol → 4-Androstene-17,19-dione

HRID 2397976Notes

Reaction equation

HRID 2397976 reaction equation
[CH3:1][C@:2]12[CH2:20][CH2:19][C@H:18]3[C@@H:7]([CH2:8][CH2:9][C:10]4[C@:15]3([CH2:16][OH:17])[CH2:14][CH2:13][CH2:12][CH:11]=4)[C@@H:6]1[CH2:5][CH2:4][C@@H:3]2[OH:21].C[C@@H]1[C@@]2(CO)C(CC[C@@H]3[C@@H]2CC[C@@]2(C)[C@H]3CC[C@@H]2O)=CCC1>>[CH3:1][C@:2]12[CH2:20][CH2:19][C@H:18]3[C@@H:7]([CH2:8][CH2:9][C:10]4[C@:15]3([CH:16]=[O:17])[CH2:14][CH2:13][CH2:12][CH:11]=4)[C@@H:6]1[CH2:5][CH2:4][C:3]2=[O:21]

Participants

3

Reactant 2

HCID 109572354-Androstene-17beta,19-diolHCID 705847581alpha-Methyl-4-androstene-17beta,19-diol

Product 1

HCID 110873974-Androstene-17,19-dione

Procedure

In the same manner, substituting 4-androstene-17β,19-diol for the 1α-methyl-4-androstene-17β,19-diol above results in the preparation of 4-androstene-17,19-dione.

Sources & evidence

ORD record
ord-dc17b358e011479f8d25c5ea7511f966
Source dataset
uspto-grants-1977_05
Patent number
US04022769

Reaction notes

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