4-Androstene-17beta,19-diol 17-propionate → 17beta-Hydroxy-4-androsten-19-one propionate

HRID 2397978Notes

Reaction equation

HRID 2397978 reaction equation
[C:1]([O:5][C@H]1CC[C@H]2[C@H]3[C@H](CC[C@]12C)[C@]1(CO)C(=CCCC1)CC3)(=[O:4])[CH2:2][CH3:3].C(O)(=O)CC.[OH:31][C@H:32]1[CH2:37][CH2:36][C@H:35]2[C@H:38]3[C@H:49]([CH2:50][CH2:51][C@:33]12[CH3:34])[C@:46]1([CH:47]=[O:48])[C:41](=[CH:42][CH2:43][CH2:44][C@@H:45]1C)[CH2:40][CH2:39]3>>[C:1]([OH:5])(=[O:4])[CH2:2][CH3:3].[OH:31][C@H:32]1[CH2:37][CH2:36][C@H:35]2[C@H:38]3[C@H:49]([CH2:50][CH2:51][C@:33]12[CH3:34])[C@:46]1([CH:47]=[O:48])[C:41](=[CH:42][CH2:43][CH2:44][CH2:45]1)[CH2:40][CH2:39]3

Participants

3

Reactant 2

HCID 706279304-Androstene-17beta,19-diol 17-propionateHCID 8673473517beta-Hydroxy-1alpha-methyl-4-androsten-19-one propionate

Product 1

HCID 8673473717beta-Hydroxy-4-androsten-19-one propionate

Procedure

Substituting 4-androstene-17β,19-diol 17-propionate for the 17β-hydroxy-1α-methyl-4-androsten-19-one propionate above results in the preparation of 17β-hydroxy-4-androsten-19-one propionate.

Sources & evidence

ORD record
ord-a4876bf835524d84a69cdf53d697b0da
Source dataset
uspto-grants-1977_05
Patent number
US04022769

Reaction notes

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