17beta-Hydroxy-1alpha-methyl-4-androsten-19-one propionate → 17beta-Hydroxy-4-androsten-19-one

HRID 2397980Notes

Reaction equation

HRID 2397980 reaction equation
C(O)(=O)CC.[OH:6][C@H:7]1[CH2:12][CH2:11][C@H:10]2[C@H:13]3[C@H:24]([CH2:25][CH2:26][C@:8]12[CH3:9])[C@:21]1([CH:22]=[O:23])[C:16](=[CH:17][CH2:18][CH2:19][CH2:20]1)[CH2:15][CH2:14]3.C(O)(=O)CC.O[C@H]1CC[C@H]2[C@H]3[C@H](CC[C@]12C)[C@]1(C=O)C(=CCC[C@@H]1C)CC3>>[OH:6][C@H:7]1[CH2:12][CH2:11][C@H:10]2[C@H:13]3[C@H:24]([CH2:25][CH2:26][C@:8]12[CH3:9])[C@:21]1([CH:22]=[O:23])[C:16](=[CH:17][CH2:18][CH2:19][CH2:20]1)[CH2:15][CH2:14]3

Participants

3

Reactant 2

HCID 8673473517beta-Hydroxy-1alpha-methyl-4-androsten-19-one propionateHCID 8673473717beta-Hydroxy-4-androsten-19-one propionate

Product 1

HCID 5429705217beta-Hydroxy-4-androsten-19-one

Procedure

Substituting 17β-hydroxy-4-androsten-19-one propionate for the 17β-hydroxy-1α-methyl-4-androsten-19-one propionate above results in the preparation of 17β-hydroxy-4-androsten-19-one.

Sources & evidence

ORD record
ord-82296c8edf8c4dcbacd7dc20b5559dae
Source dataset
uspto-grants-1977_05
Patent number
US04022769

Reaction notes

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