HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 19-Hydroxy-4-methyl-4-androstene3,17-dione acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 19-Hydroxy-4-methyl-4-androstene-3,17-dione | HCID 53795050 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 19-Hydroxy-4-methyl-4-androstene3,17-dione acetate | HCID 86734746 | — |
Reaction Steps
19-Hydroxy-4-methyl-4-androstene-3,17-dione is stirred under nitrogen with acetic anhydride and pyridine for about 16 hours. The yellow solution is poured onto water and the precipitate collected by suction filtration and washed well with water. Crystallization from acetone-hexane yields the desired 19-hydroxy-4-methyl-4-androstene-3,17-dione acetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04022769 |
| Source dataset | uspto-grants-1977_05 |
| ORD ID | ord-39c5f48a2703496d8aaea8af3010e5a5 |
| Source note | uspto-grants-1977_05 |