Potassium sodium tartarate → HCID 70584930, compound

Participants

Reaction Steps

A tetrahydrofuran solution of 19-hydroxy-4-androstene-3,17-dione acetate is added to lithium tri-t-butoxyaluminum hydride in tetrahydrofuran, and the resultant solution stirred overnight at room temperature. An aqueous solution of sodium potassium tartrate is added with stirring until a readily filterable precipitate forms. The filtrate is concentrated under reduced pressure and diluted with ether. The resulting solution is washed with water, dried over magnesium sulfate and the ether removed under vacuum. The residual androst-4-ene-3β, 17β,19-triol 19-acetate is crystallized from acetone.

Provenance & Evidence