Dichloroacetyl chloride → HCID 53711305, compound

HRID 2398128Notes

Reaction equation

HRID 2398128 reaction equation
[OH:1][N:2]=[C:3]([C:7]1[O:8][CH:9]=[CH:10][CH:11]=1)[C:4]([OH:6])=[O:5].[Cl:12][CH:13]([Cl:17])[C:14](Cl)=[O:15]>C(Cl)Cl>[Cl:12][CH:13]([Cl:17])[C:14]([O:1][N:2]=[C:3]([C:7]1[O:8][CH:9]=[CH:10][CH:11]=1)[C:4]([OH:6])=[O:5])=[O:15]

Participants

4

Reactant 2

HCID 6593Dichloroacetyl chlorideHCID 727327832-(Fur-2-yl)-2-hydroxyiminoacetic acid

Product 1

HCID 53711305HCID 53711305, compoundYield 63%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

2-Hydroxyimino-2-(fur-2-yl)acetic acid (1.38g) mixture was added portionwise to an ice cold solution of dichloroacetyl chloride (2.8 mls.) in dry methylene chloride (14 mls.). After 15 mins stirring a white precipitate was formed which was collected, washed successively with cold dry methylene chloride and petrol (b.p 40°-60°) and dried to yield 2-dichloroacetoxyimino-2-(fur-2-yl)acetic acid (syn-isomer) (1.5 g. 63%).

Workup

  1. customwas formed which
  2. customwas collected
  3. washwashed successively with cold dry methylene chloride and petrol (b.p 40°-60°)
  4. customdried

Sources & evidence

ORD record
ord-46816586eaef491d978d0b58d60d5b22
Source dataset
uspto-grants-1977_05
Patent number
US04024134

Reaction notes

Loading…