Phosphorus pentachloride → HCID 54434434, compound

HRID 2398129Notes

Reaction equation

HRID 2398129 reaction equation
[Cl:1][CH:2]([Cl:16])[C:3]([O:5][N:6]=[C:7]([C:11]1[O:12][CH:13]=[CH:14][CH:15]=1)[C:8](O)=[O:9])=[O:4].P(Cl)(Cl)(Cl)(Cl)[Cl:18]>C(Cl)Cl>[Cl:1][CH:2]([Cl:16])[C:3]([O:5][N:6]=[C:7]([C:11]1[O:12][CH:13]=[CH:14][CH:15]=1)[C:8]([Cl:18])=[O:9])=[O:4]

Participants

4

Reactant 2

HCID 24819Phosphorus pentachlorideHCID 53711305HCID 53711305, compound

Product 1

HCID 54434434HCID 54434434, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent2×

Procedure

To an ice-cold stirred suspension of 2-dichloroacetoxyimino-2-(fur-2-yl)acetic acid (1.5 g) in dry methylene chloride (70 mls) was added dropwise a freshly prepared solution of phosphorus pentachloride (1.0 equiv.) in methylene chloride. When solution was complete the solvent was evaporated at low temperature and the residual oil azeotroped with benzene to give 2-dichloroacetoxyimino-2-(fur-2-yl)acetyl chloride (syn-isomer) as a pale yellow oil which was used directly.

Workup

  1. customwas evaporated at low temperature
  2. customthe residual oil azeotroped with benzene

Sources & evidence

ORD record
ord-e74880ae2ddd42b2b683ebe70f3e8b1a
Source dataset
uspto-grants-1977_05
Patent number
US04024134

Reaction notes

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