Cyclohexyl isocyanate → HCID 21434447, compound

HRID 2398170Notes

Reaction equation

[CH2:1]([NH:5][C:6]([N:8]1[CH2:14][CH2:13][C:12]2[CH:15]=[CH:16][C:17]([S:19]([NH2:22])(=[O:21])=[O:20])=[CH:18][C:11]=2[CH2:10][CH2:9]1)=[O:7])[CH2:2][CH2:3][CH3:4].[CH:23]1([N:29]=[C:30]=[O:31])[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]1>>[CH:23]1([NH:29][C:30]([NH:22][S:19]([C:17]2[CH:16]=[CH:15][C:12]3[CH2:13][CH2:14][N:8]([C:6](=[O:7])[NH:5][CH2:1][CH2:2][CH2:3][CH3:4])[CH2:9][CH2:10][C:11]=3[CH:18]=2)(=[O:21])=[O:20])=[O:31])[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]1

Participants

Reactant 2

HCID 18502Cyclohexyl isocyanate

HCID 21434430HCID 21434430, compound

Product 1

HCID 21434447HCID 21434447, compound

Procedure

By the reaction of 3-butylcarbamoyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7-sulfonamide with cyclohexylisocyanate in a manner analogous to that described in Example 1, there is obtained 1-cyclohexyl-3-[(3-butylcarbamoyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)sulfonyl]urea. The starting material can be prepared by the reaction of 2,3,4,5-tetrahydro-1H-3-benzazepine-7-sulfonamide with butylisocyanate in a manner analogous to that described in Example 8.

Sources & evidence

ORD record: ord-1bcfbef6d4474e128dc4f3741d9d5d27
Source dataset: uspto-grants-1977_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04024128

Reaction notes

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