HCID 53895465, compound → HCID 178484660, compound

HRID 2398180Notes

Reaction equation

HRID 2398180 reaction equation
C([O:3][C:4](=O)[NH:5][S:6]([C:9]1[CH:24]=[CH:23][C:12]2[CH2:13][CH2:14][N:15]([C:18](=[O:22])[N:19]([CH3:21])[CH3:20])[CH2:16][CH2:17][C:11]=2[CH:10]=1)(=[O:8])=[O:7])C.[CH3:26][C@H:27]1[CH2:32][CH2:31][C@H:30]([NH2:33])[CH2:29][CH2:28]1>>[CH3:20][N:19]([CH3:21])[C:18]([N:15]1[CH2:14][CH2:13][C:12]2[CH:23]=[CH:24][C:9]([S:6]([NH:5][C:4]([NH:33][C@H:30]3[CH2:31][CH2:32][C@H:27]([CH3:26])[CH2:28][CH2:29]3)=[O:3])(=[O:8])=[O:7])=[CH:10][C:11]=2[CH2:17][CH2:16]1)=[O:22]

Participants

3

Reactant 2

HCID 53895465HCID 53895465, compoundHCID 178461305HCID 178461305, compound

Product 1

HCID 178484660HCID 178484660, compound

Procedure

By the reaction of [(3-dimethylcarbamoyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)sulfonyl]carbamic acid ethyl ester with trans-4-methylcyclohexylamine in a manner analogous to that described in Example 12, there is obtained 1-[(3-dimethylcarbamoyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)sulfonyl]-3-(trans-4-methylcyclohexyl)urea.

Sources & evidence

ORD record
ord-7f8010c1cd9642ebb6db06b6e807fba5
Source dataset
uspto-grants-1977_05
Patent number
US04024128

Reaction notes

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