HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → HCID 21434993, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | HCID 12801674 | HCID 12801674 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 21434993 | HCID 21434993 | — |
Reaction Steps
7-Chloro-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid (29.5 g) and thionyl chloride (18 ml) in dry toluene (900 ml) were stirred and heated under reflux for 1 hour. The solution was cooled and the solid that separated was collected. It had m.p. 186.5°-188.5° (98%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04024255 |
| Source dataset | uspto-grants-1977_05 |
| ORD ID | ord-d9cdfc69b04243d0bb418d24449f8ea9 |
| Source note | uspto-grants-1977_05 |