Glycine → L-Methionylglycine

HRID 2398320Notes

Reaction equation

HRID 2398320 reaction equation
[NH2:1][C@H:2]([C:7]([OH:9])=O)[CH2:3][CH2:4][S:5][CH3:6].[NH2:10][CH2:11][C:12]([OH:14])=[O:13]>O>[NH2:1][C@H:2]([C:7]([NH:10][CH2:11][C:12]([OH:14])=[O:13])=[O:9])[CH2:3][CH2:4][S:5][CH3:6]

Participants

4

Reactant 2

HCID 750GlycineHCID 6137L-Methionine2×

Product 1

HCID 6992930L-Methionylglycine

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

The title compound was prepared according to the procedures of Example 1A and B above by replacing DL-methionine with L-methionine (Aldrich Chemical Co., Beil. 4(2),938). The title compound had a melting point of 188° to 190° C (d). The compound was found to be water soluble. The product thus obtained was subjected to amino acid analysis and found to contain 49.42 mole percent glycine and 50.58 mole percent methionine.

Workup

  1. customThe title compound was prepared
  2. customThe product thus obtained

Sources & evidence

ORD record
ord-ec2dbd97c5644168a8e01e2b4186f3f6
Source dataset
uspto-grants-1977_05
Patent number
US04024286

Reaction notes

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