HCID 178503872, compound → HCID 178512381, compound

HRID 2398339Notes

Reaction equation

HRID 2398339 reaction equation
[NH2:1][CH2:2][CH2:3][S:4][CH2:5][C:6]1[N:7]=[CH:8][NH:9][CH:10]=1.[C:11]([NH:13][C:14](=[N:17]CCSCC1N=CNC=1)SC)#[N:12]>C(O)C>[C:11]([NH:13][C:14]([NH:1][CH2:2][CH2:3][S:4][CH2:5][C:6]1[N:7]=[CH:8][NH:9][CH:10]=1)=[NH:17])#[N:12]

Participants

4

Reactant 2

HCID 178503872HCID 178503872, compoundHCID 178511469HCID 178511469, compound

Product 1

HCID 178512381HCID 178512381, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

4-((2-Aminoethyl)thiomethyl)imidazole is reacted with dimethyl-N-cyanoimidodithiocarbonate according to the procedure of Example 3(c)(i) and the resultant N-cyano-N'-[2-(4-imidazolylmethylthio)ethyl]-S-methylisothiourea treated with ammoniacal ethanol according to the procedure of Example 5 to give the title compound.

Sources & evidence

ORD record
ord-7e41d1989ac74307bdb39ee6ca451ba3
Source dataset
uspto-grants-1977_05
Patent number
US04024271

Reaction notes

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