HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → 2(3-Aminopropylthio)imidazole dihydrobromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | 3-Amino-1-propanol | HCID 9086 | — |
| Reactant | HCID 178527877 | HCID 178527877 | — |
| Product | 2(3-Aminopropylthio)imidazole dihydrobromide | HCID 20557584 | — |
Reaction Steps
A solution of 2-mercaptoimidazole (2 g.) and 3-aminopropanol (1.14 ml.) in hydrobromic acid (48%, 25 ml.) was heated under reflux for 25 hours. The reaction mixture was evaporated to dryness and the oily residual solid recrystallised twice from ethanol/ether to give 2-(3-aminopropylthio)imidazole dihydrobromide (3.55 g.), m.p. 160°-162°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04024271 |
| Source dataset | uspto-grants-1977_05 |
| ORD ID | ord-33eb89078cfe4dd29d73bf1a1a0f870e |
| Source note | uspto-grants-1977_05 |