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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 239835Generated: October 25, 2026

N-Acetylsulfanilyl chloride → N-[4-(2-Benzoyl-4-chloro-phenylsulfamoyl)-phenyl]-acetamide

https://huagongshe.com/reaction/239835

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-Acetylsulfanilyl chlorideHCID 8481—
Reactant2-Amino-5-chlorobenzophenoneHCID 12870—
ProductN-[4-(2-Benzoyl-4-chloro-phenylsulfamoyl)-phenyl]-acetamideHCID 3481101—

Reaction Steps

The title compound was prepared according to the general procedure for the synthesis of N-Aryl-benzenesulfonamides previously described using 115 mg of (2-amino-5-chloro-phenyl)-phenyl-methanone and 117 mg of 4-Acetylamino-benzenesulfonyl chloride. 1H-NMR (400 MHz, CDCl3): δ 2.16 (s, 3H), 7.26 (b, 1H), 7.33 (d, 1H, J=2.4 Hz), 7.39 (m, 6H), 7.46 (dd, 1H, J=8.4 Hz, 2.4 Hz), 7.55 (m, 3H), 7.71 (d, 1H, J=8.8 Hz), 9.74 (s, 1H). MS: m/z 429.0 (M++1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08642808B2
Source datasetuspto-grants-2014_02
ORD IDord-4ab833ec2faa485e9bae7c586bda6bfa
Source noteuspto-grants-2014_02