Ethylenediamine → N-(3-pyridazinylmethyl)ethylenediamine

HRID 2398377Notes

Reaction equation

[CH2:1]([NH2:4])[CH2:2][NH2:3].Cl[CH2:6][C:7]1[N:8]=[N:9][CH:10]=[CH:11][CH:12]=1>>[N:9]1[CH:10]=[CH:11][CH:12]=[C:7]([CH2:6][NH:3][CH2:2][CH2:1][NH2:4])[N:8]=1

Participants

Reactant 2

HCID 3301Ethylenediamine

HCID 142397123-(Chloromethyl)pyridazine

Product 1

HCID 21698444N-(3-pyridazinylmethyl)ethylenediamine

Procedure

Reacting ethylenediamine with 3-chloromethylpyridazine by the procedure of Example 34 gives N-(3-pyridazinylmethyl)ethylenediamine. This intermediate is reacted with S-methylisothiouronium sulphate by the procedure of Example 1 to give the title compound.

Sources & evidence

ORD record: ord-cbfb012608a749d488fac56ef85a0e54
Source dataset: uspto-grants-1977_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04024271

Reaction notes

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