2-((Isoxazol-3-ylmethyl)thio)ethanamine → HCID 178512218, compound

HRID 2398408Notes

Reaction equation

HRID 2398408 reaction equation
[NH2:1][CH2:2][CH2:3][S:4][CH2:5][C:6]1[CH:10]=[CH:9][O:8][N:7]=1.CS[C:13](=[NH:18])[NH:14][N+:15]([O-:17])=[O:16]>>[N+:15]([NH:14][C:13]([NH:1][CH2:2][CH2:3][S:4][CH2:5][C:6]1[CH:10]=[CH:9][O:8][N:7]=1)=[NH:18])([O-:17])=[O:16]

Participants

3

Reactant 2

HCID 129234172-((Isoxazol-3-ylmethyl)thio)ethanamineHCID 135927615N-Nitro-S-methylisothiourea

Product 1

HCID 178512218HCID 178512218, compound

Procedure

Reacting 3-[(2-aminoethyl)thiomethyl]isoxazole with S-methyl-N-nitroisothiourea by the procedure of Example 2(ii) gives N-nitro-N'-[2-(3-isoxazolylmethylthio)ethyl]guanidine.

Sources & evidence

ORD record
ord-07c3215cdece40eca02eb8e06fe7cb22
Source dataset
uspto-grants-1977_05
Patent number
US04024271

Reaction notes

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