HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylenediamine → N-(2-thiazolylmethyl)ethylenediamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylenediamine | HCID 3301 | — |
| Reactant | 2-(Chloromethyl)-1,3-thiazole | HCID 14090864 | — |
| Product | N-(2-thiazolylmethyl)ethylenediamine | HCID 17944882 | — |
Reaction Steps
Reacting ethylenediamine with 2-chloromethylthiazole by the procedure of Example 34 gives N-(2-thiazolylmethyl)ethylenediamine. Reacting this intermediate with S-methyl-N-nitroisothiourea by the procedure of Example 2(ii) gives N-nitro-N'-[2-(2-thiazolylmethylamino)ethyl]guanidine. Treatment with hydrobromic acid gives the hydrobromide salt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04024271 |
| Source dataset | uspto-grants-1977_05 |
| ORD ID | ord-3e911deffc2c469a8b99f1f97040cdfd |
| Source note | uspto-grants-1977_05 |