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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2398410Generated: October 31, 2026

Ethylenediamine → HCID 178484974, compound

https://huagongshe.com/reaction/2398410

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthylenediamineHCID 3301—
Reactant1-Cyano-2,3-dimethylisothioureaHCID 111103—
Reactant2-(Chloromethyl)-1,3-thiazoleHCID 14090864—
ReactantN-(2-thiazolylmethyl)ethylenediamineHCID 17944882—
ProductHCID 178484974HCID 178484974—

Reaction Steps

Reacting ethylenediamine with 2-chloromethylthiazole by the procedure of Example 34, then reacting the resulting N-(2-thiazolylmethyl)ethylenediamine with N-cyano-N',S-dimethylisothiourea by the procedure of Example 3(a), gives N-cyano-N'-methyl-N"-[2-(2-thiazolylmethylamino)ethyl]guanidine. Hydrolysis of this compound by the procedure of Example 3(e) gives N-methyl-N'-[2-(2-thiazolylmethylamino)ethyl]guanidine trihydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04024271
Source datasetuspto-grants-1977_05
ORD IDord-674f4e250fe146469b8b04a88bdbc447
Source noteuspto-grants-1977_05