Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2398416Generated: November 2, 2026

Thionyl Chloride → 5-Benzyl-4-chloromethyloxazole

https://huagongshe.com/reaction/2398416

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThionyl ChlorideHCID 24386—
ReactantHCID 15555621HCID 15555621—
Product5-Benzyl-4-chloromethyloxazoleHCID 20557836—

Reaction Steps

5-Benzyl-4-oxazolecarboxylic acid is converted to 5-benzyl-4-hydroxymethyl xazole by the procedure of Example 135. Treating this hydroxylmethyl compound with thionyl chloride gives 5-benzyl-4-chloromethyloxazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04024271
Source datasetuspto-grants-1977_05
ORD IDord-7d708ceb34ff43dc86ad83f40cbcad72
Source noteuspto-grants-1977_05