1,3-Propanediamine → HCID 178483804, compound

HRID 2398427Notes

Reaction equation

HRID 2398427 reaction equation
NC[CH2:3][CH2:4][NH:5][CH2:6][C:7]1[NH:8][C:9]2[CH:15]=[CH:14][CH:13]=[CH:12][C:10]=2[N:11]=1.ClC[C:18]1[NH:19][C:20]2C=CC=CC=2N=1.NCCCN.CN=C=S.N1C2C=CC=CC=2NC=1CNC[CH2:48][CH2:49][NH:50][C:51]([NH:54][C:55]#[N:56])=[N:52]C>>[N:8]1[C:9]2[CH:15]=[CH:14][CH:13]=[CH:12][C:10]=2[NH:11][C:7]=1[CH2:6][NH:5][CH2:4][CH2:3][NH:52][C:51]([NH:54][C:55]#[N:56])=[N:50][CH2:49][CH2:48][N:19]([CH3:20])[CH3:18]

Participants

6

Reactant 5

HCID 4281,3-PropanediamineHCID 11167Methyl isothiocyanateHCID 785712-ChloromethylbenzimidazoleHCID 20567598HCID 20567598, compoundHCID 53702203HCID 53702203, compound

Product 1

HCID 178483804HCID 178483804, compound

Procedure

Using in the above procedure, 2-[(3-aminopropyl)aminomethyl]benzimidazole prepared by reacting 2-chloromethylbenzimidazole with 1.3-diaminopropane) and methyl isothiocyanate, the product is N-[3-(2-benzimidazolylmethylamino)propyl]-N'-cyano-N"-methylguanidine.

Workup

  1. customprepared

Sources & evidence

ORD record
ord-6c67b2f3e7744a9d81f01eca9f57e4f5
Source dataset
uspto-grants-1977_05
Patent number
US04024271

Reaction notes

Loading…