Cysteamine Hydrochloride → 5H,6H,7H,8H-imidazo(1,5-a)pyridine

HRID 2398430Notes

Reaction equation

OC[C:3]1[N:7]2[CH2:8][CH2:9][CH2:10][CH2:11][C:6]2=[CH:5][N:4]=1.Cl.NCCS>>[CH:5]1[N:4]=[CH:3][N:7]2[CH2:8][CH2:9][CH2:10][CH2:11][C:6]=12

Participants

Reactant 2

HCID 9082Cysteamine Hydrochloride

HCID 12923422(5,6,7,8-Tetrahydroimidazo[1,5-a]pyridin-3-yl)methanol

Product 1

HCID 141931035H,6H,7H,8H-imidazo(1,5-a)pyridine

Procedure

Reacting 3-hydroxymethyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine with cysteamine hydrochloride by the procedure of Example 1 gives 3-[2-aminoethyl)thiomethyl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine.

Sources & evidence

ORD record: ord-278105c709584eb6900f2e63953d9cc2
Source dataset: uspto-grants-1977_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04024271

Reaction notes

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