3-Chloro-N,N-dimethyl-1-propanamine → 3-[4-(3-Dimethylaminopropoxy)benzoyl]-2-phenylbenzofuran

HRID 2398442Notes

Reaction equation

HRID 2398442 reaction equation
[OH:1][C:2]1[CH:24]=[CH:23][C:5]([C:6]([C:8]2[C:12]3[CH:13]=[CH:14][CH:15]=[CH:16][C:11]=3[O:10][C:9]=2[C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[O:7])=[CH:4][CH:3]=1.[CH3:25][N:26]([CH3:31])[CH2:27][CH2:28][CH2:29]Cl>>[CH3:25][N:26]([CH3:31])[CH2:27][CH2:28][CH2:29][O:1][C:2]1[CH:3]=[CH:4][C:5]([C:6]([C:8]2[C:12]3[CH:13]=[CH:14][CH:15]=[CH:16][C:11]=3[O:10][C:9]=2[C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=2)=[O:7])=[CH:23][CH:24]=1

Participants

3

Reactant 2

HCID 669603-Chloro-N,N-dimethyl-1-propanamineHCID 13264991(4-Hydroxyphenyl)(2-phenyl-1-benzofuran-3-yl)methanone

Product 1

HCID 214353393-[4-(3-Dimethylaminopropoxy)benzoyl]-2-phenylbenzofuran

Procedure

When 3-(4-hydroxybenzoyl)-2-phenylbenzofuran is reacted with 3-dimethylaminopropyl chloride by the procedure described in Example 1, 3-[4-(3-dimethylaminopropoxy)benzoyl]-2-phenylbenzofuran is obtained.

Sources & evidence

ORD record
ord-97faed4b8bed4b0d8a03bb1d9dd3b7e4
Source dataset
uspto-grants-1977_05
Patent number
US04024273

Reaction notes

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