HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 4-(2-Diethylaminoethoxy)benzoyl chloride hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4-[2-(Diethylamino)ethoxy]benzoic acid hydrochloride | HCID 42937492 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-(2-Diethylaminoethoxy)benzoyl chloride hydrochloride | HCID 16111875 | — |
Reaction Steps
4-(2-Diethylaminoethoxy)benzoic acid hydrochloride is suspended in methylene chloride and a five-fold excess of thionyl chloride is added. The mixture is refluxed until the solid dissolves, then concentrated under reduced pressure to give 4-(2-diethylaminoethoxy)benzoyl chloride hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04024273 |
| Source dataset | uspto-grants-1977_05 |
| ORD ID | ord-ab3961a2faf44469b1ac94b0d17982ee |
| Source note | uspto-grants-1977_05 |