5-Chloro-2-phenylbenzofuran → 5-Chloro-3-[2-(2-diethylaminoethoxy)benzoyl]-2-phenylbenzofuran

HRID 2398454Notes

Reaction equation

HRID 2398454 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[O:9][C:8]([C:10]3[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=3)=[CH:7][C:6]=2[CH:16]=1.Cl.[CH2:18]([N:20]([CH2:33][CH3:34])[CH2:21][CH2:22][O:23][C:24]1[CH:32]=[CH:31][CH:30]=[CH:29][C:25]=1[C:26](Cl)=[O:27])[CH3:19]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[O:9][C:8]([C:10]3[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=3)=[C:7]([C:26](=[O:27])[C:25]3[CH:29]=[CH:30][CH:31]=[CH:32][C:24]=3[O:23][CH2:22][CH2:21][N:20]([CH2:33][CH3:34])[CH2:18][CH3:19])[C:6]=2[CH:16]=1

Participants

3

Reactant 2

HCID 6150425-Chloro-2-phenylbenzofuranHCID 214352662-(2-Diethylaminoethoxy)benzoyl chloride hydrochloride

Product 1

HCID 214353845-Chloro-3-[2-(2-diethylaminoethoxy)benzoyl]-2-phenylbenzofuran

Procedure

Acylation of 5-chloro-2-phenylbenzofuran with 2-(2-diethylaminoethoxy)benzoyl chloride hydrochloride by the procedure described in Example 6 gives the title compound.

Sources & evidence

ORD record
ord-34a79d11873d477aacb7ece037aad56d
Source dataset
uspto-grants-1977_05
Patent number
US04024273

Reaction notes

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