2-(4-Chlorophenyl)-1-benzofuran → 2-(4-Chlorophenyl)-3-[4-(3-diethylaminopropoxy)benzoyl]benzofuran

HRID 2398455Notes

Reaction equation

HRID 2398455 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]3[CH:16]=[CH:15][CH:14]=[CH:13][C:11]=3[CH:12]=2)=[CH:4][CH:3]=1.Cl.[CH2:18]([N:20]([CH2:34][CH3:35])[CH2:21][CH2:22][CH2:23][O:24][C:25]1[CH:33]=[CH:32][C:28]([C:29](Cl)=[O:30])=[CH:27][CH:26]=1)[CH3:19]>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]3[CH:16]=[CH:15][CH:14]=[CH:13][C:11]=3[C:12]=2[C:29](=[O:30])[C:28]2[CH:27]=[CH:26][C:25]([O:24][CH2:23][CH2:22][CH2:21][N:20]([CH2:34][CH3:35])[CH2:18][CH3:19])=[CH:33][CH:32]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 43683122-(4-Chlorophenyl)-1-benzofuranHCID 214353144-(3-Diethylaminopropoxy)benzoyl chloride hydrochloride

Product 1

HCID 214352742-(4-Chlorophenyl)-3-[4-(3-diethylaminopropoxy)benzoyl]benzofuran

Procedure

When 2-(p-chlorophenyl)benzofuran is acylated with 4-(3-diethylaminopropoxy)benzoyl chloride hydrochloride by the procedure described in Example 6, the title compound is obtained.

Sources & evidence

ORD record
ord-5cfaad342f264df0a2a510f44dc0ef93
Source dataset
uspto-grants-1977_05
Patent number
US04024273

Reaction notes

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