2-(4-Methoxyphenyl)benzofuran → 3-[4-(3-Diethylaminopropoxy)benzoyl]-2-(4-methoxyphenyl)benzofuran

HRID 2398456Notes

Reaction equation

HRID 2398456 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[O:10][C:11]3[CH:17]=[CH:16][CH:15]=[CH:14][C:12]=3[CH:13]=2)=[CH:5][CH:4]=1.Cl.[CH2:19]([N:21]([CH2:35][CH3:36])[CH2:22][CH2:23][CH2:24][O:25][C:26]1[CH:34]=[CH:33][C:29]([C:30](Cl)=[O:31])=[CH:28][CH:27]=1)[CH3:20]>>[CH2:35]([N:21]([CH2:19][CH3:20])[CH2:22][CH2:23][CH2:24][O:25][C:26]1[CH:27]=[CH:28][C:29]([C:30]([C:13]2[C:12]3[CH:14]=[CH:15][CH:16]=[CH:17][C:11]=3[O:10][C:9]=2[C:6]2[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=2)=[O:31])=[CH:33][CH:34]=1)[CH3:36]

Participants

3

Reactant 2

HCID 107278342-(4-Methoxyphenyl)benzofuranHCID 214353144-(3-Diethylaminopropoxy)benzoyl chloride hydrochloride

Product 1

HCID 214352783-[4-(3-Diethylaminopropoxy)benzoyl]-2-(4-methoxyphenyl)benzofuran

Procedure

Acylation of 2-(p-methoxyphenyl)benzofuran with 4-(3-diethylaminopropoxy)benzoyl chloride hydrochloride by the procedure described in Example 6 gives the title compound.

Sources & evidence

ORD record
ord-4bcec43499d84da7b62c3a28bac957cf
Source dataset
uspto-grants-1977_05
Patent number
US04024273

Reaction notes

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