反应详情

A solution of 27.2 g. (0.14 mol.) of 3,5-diethyl-4-hydroxybenzoic acid in 200 ml. of methanol containing 2 ml. of sulfuric acid is refluxed for 12 hours. After cooling, excess methanol is evaporated, water is added to the residue and it is made basic with 10% aqueous sodium hydroxide. The precipitate is collected, washed with water and dried in vacuo to give 3,5-diethyl-4-hydroxybenzoic acid methyl ester.

1. temperatureAfter cooling
2. customexcess methanol is evaporated
3. additionwater is added to the residue and it
4. customThe precipitate is collected
5. washwashed with water
6. customdried in vacuo