3-Chloropropyl(diethyl)amine → HCID 21435272, compound

HRID 2398493Notes

Reaction equation

HRID 2398493 reaction equation
[C:1]1([C:7]2[O:8][C:9]3[CH:15]=[CH:14][CH:13]=[CH:12][C:10]=3[CH:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:16]([C:18]1[CH:19]=[C:20]([CH:24]=[C:25]([CH2:29][CH3:30])[C:26]=1[O:27][CH3:28])[C:21](Cl)=[O:22])[CH3:17].[CH2:31]([N:33]([CH2:38][CH3:39])[CH2:34][CH2:35][CH2:36]Cl)[CH3:32]>>[CH2:29]([C:25]1[CH:24]=[C:20]([CH:19]=[C:18]([CH2:16][CH3:17])[C:26]=1[O:27][CH3:28])[C:21]([C:11]1[C:10]2[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=2[O:8][C:7]=1[C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)=[O:22])[CH3:30].[CH2:29]([C:25]1[CH:24]=[C:20]([CH:19]=[C:18]([CH2:16][CH3:17])[C:26]=1[O:27][CH2:36][CH2:35][CH2:34][N:33]([CH2:38][CH3:39])[CH2:31][CH3:32])[C:21]([C:11]1[C:10]2[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=2[O:8][C:7]=1[C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)=[O:22])[CH3:30]

Participants

5

Reactant 3

HCID 669183-Chloropropyl(diethyl)amineHCID 35179362-Phenyl-benzofuranHCID 21435360HCID 21435360, compound

Product 2

HCID 21435272HCID 21435272, compoundHCID 21435331HCID 21435331, compound

Procedure

3-(3,5-Diethyl-4-methoxybenzoyl)-2-phenylbenzofuran is prepared by acylation of 2-phenylbenzofuran with 3,5-diethyl-4-methoxybenzoyl chloride as described above. The subsequent steps of demethylation and reaction with 3-diethylaminopropyl chloride to give the title compound are accomplished as previously described.

Sources & evidence

ORD record
ord-2919afb69fac4ff29027d677cbdff907
Source dataset
uspto-grants-1977_05
Patent number
US04024273

Reaction notes

Loading…