HCID 178465155, compound → HCID 178468101, compound

Participants

Reaction Steps

In analogy to Example 1 f), 500 mg of Glu-His-Trp-NH-NH2 were reacted with 920 mg (1 mmole) of H-Ser-Tyr-D-Glu(OBut)-Leu-Arg-Pro-NH-C2H5 . 2 HCl and purified chromatographically. Yield: 491.5 mg of chromatographically pure material. The content of peptide base was 79% as per UV-spectrum (yield: 30%). [-α]D22 = -31.3° (c=1, dimethyl acetamide)

Provenance & Evidence