HCID 68120100, compound → HCID 70621330, compound

Participants

Reaction Steps

The mixture of 0.75 g of N-(4-benzyloxycarbonylamino-o-tolyl)-4-chlorophthalimide 100 ml of ethyl acetate and 0.1 g of 10% palladium on charcoal is hydrogenated at 2.5 atm. and room temperature for 4 hours whereby the intermediarily formed carbaminic acid decarboxylates. The mixture is filtered, the filtrate concentrated to 10 ml and the precipitate formed collected, to yield the N-(4-amino-o-tolyl)-4-chlorophthalimide melting at 202°-204°.

Provenance & Evidence