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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2398640Generated: October 30, 2026

Ethylparaben → HCID 19069386, compound

https://huagongshe.com/reaction/2398640

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthylparabenHCID 8434—
ReactantPotassium CarbonateHCID 11430—
Reactant2-ChlorothiazoleHCID 76429—
SolventDimethylformamideHCID 6228—
ProductHCID 19069386HCID 1906938627.8%

Reaction Steps

A mixture of 2-chlorothiazole (2.0 g), ethyl 4-hydroxybenzoate (2.8 g), potassium carbonate powder (3.5 g) and dimethylformamide (30 ml) is stirred at 135°-140° C. for 6 hours. The reaction mixture is treated in the same manner as in Example 1. From the eluate of 30% ether-benzene, ethyl 4-(2-thiazolyloxy)benzoate (1.16 g) is obtained. IR νmaxCCl4 1730, 1280 cm-1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04025528
Source datasetuspto-grants-1977_05
ORD IDord-f77c549bd77844e2bee66b1c3140920c
Source noteuspto-grants-1977_05