HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Methylaniline → ethyl 2-(N-methylanilino)-4-thiazolylacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Methylaniline | HCID 7515 | — |
| Reactant | Ethyl 2-(2-bromo-1,3-thiazol-4-yl)acetate | HCID 53428667 | — |
| Product | ethyl 2-(N-methylanilino)-4-thiazolylacetate | HCID 53687162 | 90.5% |
Reaction Steps
A mixture of ethyl 2-bromo-4-thiazolylacetate (2.5 g) and N-methylaniline (2.1 g) is stirred at 150°-155° C. for 30 minutes. The resultant solution is treated in the same manner as in Example 1 to give ethyl 2-(N-methyl-anilino)-4-thiazolylacetate (2.5 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04025528 |
| Source dataset | uspto-grants-1977_05 |
| ORD ID | ord-c2910bcec9074ce6ba00432e9b269faf |
| Source note | uspto-grants-1977_05 |