2-{[(3-Bromopyridin-2-yl)methyl]sulfanyl}ethan-1-amine → HCID 178512223, compound

HRID 2398683Notes

Reaction equation

HRID 2398683 reaction equation
BrC1C(CSCCN)=NC=CC=1.C([NH:21][C:22]([NH:35][CH2:36][CH2:37][S:38][CH2:39][C:40]1[C:45]([Br:46])=[CH:44][CH:43]=[CH:42][N:41]=1)=[N:23][CH2:24][CH2:25][S:26][CH2:27][C:28]1[C:33]([Br:34])=[CH:32][CH:31]=[CH:30][N:29]=1)(=O)C1C=CC=CC=1>N1C=CC=CC=1>[Br:46][C:45]1[C:40]([CH2:39][S:38][CH2:37][CH2:36][NH:35][C:22]([NH:23][CH2:24][CH2:25][S:26][CH2:27][C:28]2[C:33]([Br:34])=[CH:32][CH:31]=[CH:30][N:29]=2)=[NH:21])=[N:41][CH:42]=[CH:43][CH:44]=1

Participants

4

Reactant 2

HCID 129515272-{[(3-Bromopyridin-2-yl)methyl]sulfanyl}ethan-1-amineHCID 54262795N-benzoyl-N',N"-bis-[2-((3-bromo-2-pyridyl)methylthio)ethyl]guanidine

Product 1

HCID 178512223HCID 178512223, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

The reaction of 3-bromo-2-[(2-aminoethyl)thiomethyl]-pyridine with N-benzoyl-bis-dimethylthiomidocarbonate in pyridine by the method described in Example 12 yielded N-benzoyl-N',N"-bis-[2-((3-bromo-2-pyridyl)-methylthio)ethyl]guanidine which, on acid hydrolysis, yielded the title compound.

Sources & evidence

ORD record
ord-092789c87fe045b599d87006e261604b
Source dataset
uspto-grants-1977_05
Patent number
US04025527

Reaction notes

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