4-hydroxymethyl-5-methyl-1H-imidazole → HCID 178458023, compound
Reaction equation
O[CH2:2][C:3]1[N:4]=[CH:5][NH:6][C:7]=1[CH3:8].[SH:9][CH2:10][CH:11]([NH2:14])[CH2:12][CH3:13]>>[CH3:8][C:7]1[N:6]=[CH:5][NH:4][C:3]=1[CH2:2][S:9][CH2:10][CH:11]([NH2:14])[CH2:12][CH3:13]Participants
3
Procedure
Reaction of 4-hydroxymethyl-5-methylimidazole and 1-mercapto-2-aminobutane in the procedure of Example 1(i) yields 4-methyl-5-[(2-aminobutyl)thiomethyl]imidazole and, when this is reacted with S-methyl-N'-[2-((4-methyl 5-imidazolyl)methylthio)ethyl]thiouronium sulphate in the procedure of Example 1(iii), the title compound is produced.
Sources & evidence
- ORD record
- ord-2d793e3d704946a2951b43225ef2772b
- Source dataset
- uspto-grants-1977_05
- Patent number
- US04025527
Reaction notes
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