6-Amino-1,3-dimethyluracil → HCID 22797766, compound

Participants

Reaction Steps

To 10 ml of anhydrous xylene were added 390 mg (1 mmol) of 2,3,4,6-tetra-O-acetyl-D-glucopyranosyl isothiocyanate and 140 mg (1 mmol) of 6-amino-1,3-dimethyluracil (MW 155) and the mixture was heated on an oil bath under reflux for 9-10 hours and allowed to cool to room temperature. Crystals formed were filtered off and recrystallized from ethanol to give colourless needles melting between 171° and 173° C. (uncorrected). Yield: 240 mg (43%).

Provenance & Evidence