4-Aminoantipyrine → HCID 22797767, compound

Participants

Reaction Steps

To 5 ml of anhydrous benzene were added 390 mg (1 mmol) of 2,3,4,6-tetra-O-acetyl-D-glucopyranosyl isothiocyanate and 200 mg (1 mmol) of 4-aminoantipyrine and the mixture was heated at 60°-70° C. for 4 hours and allowed to cool to room temperature. Crystals formed were filtered off and recrystallized from petroleum ether to give pure crystals melting between 148° and 150° C. (uncorrected). Yield: 300 mg (61%).

Provenance & Evidence