HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → 5-Benzoxazoleacetic acid, 2-phenyl-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Methane | HCID 297 | — |
| Reactant | HCID 21434017 | HCID 21434017 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | 5-Benzoxazoleacetic acid, 2-phenyl- | HCID 37928 | — |
Reaction Steps
A solution of α-hydroxy-2-phenyl-5-benzoxazolyl-acetonitrile (2 g.) in acetic acid (30 ml.) containing palladium or charcoal was hydrogenated for 4 hours. The catalyst was filtered off and the solution was evaporated to dryness. The residue was recrystallised to give pure 2-phenyl-5-benzoxazolylacetic acid m.p. 175° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04025636 |
| Source dataset | uspto-grants-1977_05 |
| ORD ID | ord-ace5b03aa5ab4d35906bed6526170fa3 |
| Source note | uspto-grants-1977_05 |