Acetyl chloride → HCID 21434018, compound

HRID 2398748Notes

Reaction equation

HRID 2398748 reaction equation
ClC1C=CC([C:8]2[O:9][C:10]3[CH:16]=[CH:15][C:14]([CH:17]([OH:21])[C:18]([OH:20])=[O:19])=[CH:13][C:11]=3[N:12]=2)=CC=1.[C:22]([Cl:25])(=O)[CH3:23]>>[C:10]([O:21][C:17]([C:23]1[CH:16]=[CH:15][CH:14]=[CH:13][C:22]=1[Cl:25])([C:14]1[CH:15]=[CH:16][C:10]2[O:9][CH:8]=[N:12][C:11]=2[CH:13]=1)[C:18]([OH:20])=[O:19])(=[O:9])[CH3:11]

Participants

3

Reactant 2

HCID 6367Acetyl chlorideHCID 53840559HCID 53840559, compound

Product 1

HCID 21434018HCID 21434018, compound

Procedure

A mixture of 2-p-chlorophenyl-5-benzoxazolylglycolic acid (4 g.) and acetyl chloride (50 ml.) was heated under reflux for 24 hours. The residue on evaporation was crystallised to give pure α-acetoxy-2-chlorophenyl-5-benzoxazolylacetic acid.

Workup

  1. temperaturewas heated
  2. temperatureunder reflux for 24 hours
  3. customThe residue on evaporation
  4. customwas crystallised

Sources & evidence

ORD record
ord-345091e71006487ba0408a81d9af1cfb
Source dataset
uspto-grants-1977_05
Patent number
US04025636

Reaction notes

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