HCID 21434078, compound → HCID 178467273, compound

HRID 2398763Notes

Reaction equation

HRID 2398763 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[C:4]([NH:9][C:10](=[O:14])[CH:11]([CH3:13])[CH3:12])[CH:3]=1.[C:15]([C:18]1[C:19](=[O:29])[O:20][C:21]([OH:28])=[C:22]([C:25](=O)[CH3:26])[C:23]=1[OH:24])(=[O:17])[CH3:16]>CO>[C:15]([C:18]1[C:19](=[O:29])[O:20][C:21](=[O:28])[C:22](=[C:25]([NH:1][C:2]2[CH:7]=[CH:6][C:5]([OH:8])=[C:4]([NH:9][C:10](=[O:14])[CH:11]([CH3:12])[CH3:13])[CH:3]=2)[CH3:26])[C:23]=1[OH:24])(=[O:17])[CH3:16]

Participants

4

Reactant 2

HCID 21434078HCID 21434078, compoundHCID 1354659693,5-Diacetyl-2,6-dihydroxy-4h-pyran-4-one

Product 1

HCID 178467273HCID 178467273, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

This phenol (0.86 g., 0.0045 mol) is refluxed with 3,5-diacetyl-4,6-dihydroxy-2H-pyran-2-one (0.96 g.) in 50 ml. of methanol for 10 hours. The reaction mixture is filtered and the solid is recrystallized from ethanol to furnish 5-acetyl-4-hydroxy-3-[1-(3-isobutyramido-4-hydroxyphenylamino)ethylidene]-2H-pyran-2,6(3H)-dione, m.p. 208°-209° C. (dec.).

Workup

  1. filtrationThe reaction mixture is filtered
  2. customthe solid is recrystallized from ethanol

Sources & evidence

ORD record
ord-a2c8d2ec554442818001569c0dd1947a
Source dataset
uspto-grants-1977_05
Patent number
US04025642

Reaction notes

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