n-(5-Amino-2-methoxyphenyl)acetamide → HCID 178492262, compound

HRID 2398767Notes

Reaction equation

HRID 2398767 reaction equation
[C:1]([NH:4][C:5]1[CH:6]=[C:7]([CH:9]=[CH:10][C:11]=1[O:12][CH3:13])[NH2:8])(=[O:3])[CH3:2].[C:14]([C:17]1[C:18](=[O:28])[O:19][C:20]([OH:27])=[C:21]([C:24](=O)[CH3:25])[C:22]=1[OH:23])(=[O:16])[CH3:15]>CO>[C:1]([NH:4][C:5]1[CH:6]=[C:7]([NH:8][C:24](=[C:21]2[C:22]([OH:23])=[C:17]([C:14](=[O:16])[CH3:15])[C:18](=[O:28])[O:19][C:20]2=[O:27])[CH3:25])[CH:9]=[CH:10][C:11]=1[O:12][CH3:13])(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 267867n-(5-Amino-2-methoxyphenyl)acetamideHCID 1354659693,5-Diacetyl-2,6-dihydroxy-4h-pyran-4-one

Product 1

HCID 178492262HCID 178492262, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The aniline thus prepared (0.8 g., 0.0045 mol) is added to a hot suspension of 3,5-diacetyl-4,6-dihydroxy-2H-pyran-2-one in 50 ml. of methanol. The mixture is refluxed for one hour and filtered to obtain 3-[1-(3-acetamido-4-methoxyphenylamino)ethylidene]-5-acetyl-4-hydroxy-2H-pyran-2,6(3H)-dione, m.p. 252°-253° C. (dec.).

Workup

  1. temperatureThe mixture is refluxed for one hour
  2. filtrationfiltered

Sources & evidence

ORD record
ord-cf893c430dbb4686a9815d1041541956
Source dataset
uspto-grants-1977_05
Patent number
US04025642

Reaction notes

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